Synapse’s Core Ingredients

This compound is derived from a naturally occurring amino acid primarily found in melons combined with an organic acid found predominantly in apples. Citrulline supplementation can improve blood flow and reduces fatigue. It also increases the amount of energy your cells have to work with on a fundamental level by upping the rate at which your body’s cells can produce ATP, which is used by every cell in your body for energy.

Synapse contains a highly soluble and bioavailable form of creatine, a substance that helps your cells produce energy and is arguably the most well-researched supplement of all time. It increases the rate of blood flow in your body to help all of our other ingredients get to your brain at a faster rate, which is why a can of Synapse works so quickly. It also works along with citrulline malate to increase the rate at which you can produce ATP on a cellular level.

Alpha lipoic acid is found in high concentrations in leafy green vegetables such as spinach and broccoli. It has been implied in reducing the amount of damage incurred by neurons from oxygen use during normal operation, which helps to mitigate some of the underlying causes of age-related cognitive decline. It also plays an important role in energy metabolism, a role it fulfills through its powerful antioxidant properties and its ability to increase the amount of oxygen consumed by the body. This increase is important because the brain uses roughly a quarter of the body’s oxygen supply.

Every can of Synapse contains a touch of organic dark agave nectar, which acts as more than a sweetener. These simple carbohydrates are used as fuel to replenish the ion balance of the billions of neurons in the human brain. Agave nectar is composed mostly of fructose (a basic form of carbohydrate) which is quick to absorb, easy to digest, and enhances ATP production.

This ancient moss helps prevent your brain from breaking down the acetylcholine that has already been released. Huperzia Serrata is an acetylcholinesterase inhibitor that diminishes the breakdown of acetylcholine. Acetylcholine is a compound that functions as a neurotransmitter, and higher levels of it have been implied in increased memory retention. One of the most effective ways to increase acetylcholine in the brain is to reduce the speed with which the brain can remove it once it’s been used to send a signal, which ensures the signal sticks around long enough to be “heard.”

Commonly known as water hyssop, this ancient aquatic herb is effective as an activator of choline acetyltransferase. It increases the rate at which your brain can produce new acetylcholine. It also slightly increases the amount of acetylcholine each neuron releases in response to a stimulus. When paired with Huperzia Serrata, its effects on the brain’s cholinergic pathways are profound and overwhelmingly positive.

Found naturally within the brain as well as in soybeans and sunflowers, Alpha-GPC is a source of choline, which is one of the necessary building blocks for the creation of the neurotransmitter acetylcholine. It also works to mildly increase the amount of acetylcholine that is released by neurons, properties which work to strongly support the effects of our other cholinergic ingredients, huperzia serrata and bacopa monnieri.

This berry has long been used in both Chinese and Russian culture to combat fatigue and promote feelings of wellness. These feelings come from its properties as a potent antioxidant as well as its ability to reduce circulating levels of stress hormones such as corticosterone. It also works to increase blood flow to all areas of the body and is a mild acetylcholinesterase inhibitor, which only increases the synergy of our blend even further.

L-Theanine, naturally found in both green tea and your brain, has been shown to reduce the increase in blood pressure that many people experience in stressful situations. It works to reduce anxiety by being structurally similar enough to glutamate, the brain’s most prevalent excitatory neurotransmitter, to bind to the same cells, but just different enough that it actually blocks the excitatory effects. This promotes a feeling of calmness and well-being that is well-documented. All of these effects combine to mildly increase focus and attention, attributed to the fact that most people tend to perform better in a state of relaxed alertness.

Also known by its abbreviation, ALCAR, this potent amino acid has been demonstrated to have positive overall effects on markers of learning. It is capable of increasing the levels of a number of different neurotransmitters (particularly acetylcholine) as well as up-regulating the production of energy in cells and improving the overall function and efficiency of mitochondria (where respiration and cellular energy production occur).